Osteopathic Research Center

dr. licciardone reviewing a document with the surgeon general

Dr. Licciardone presenting osteopathic research data to former U.S. Surgeon General Regina Benjamin.

a doctor at a microscope

Dr. Hodge conducting lymphatic pump research in her laboratory.

The Osteopathic Research Center (ORC) was founded in 2002 to serve as a profession-wide research center for osteopathic medicine. The original mission of the ORC was to conduct research on the mechanistic and clinical aspects of osteopathic manipulative treatment (OMT). In so doing, the ORC has provided important evidence through systematic reviews, meta-analyses, and randomized controlled trials. The OSTEOPATHIC Trial, completed in 2011 and involving 455 patients with chronic low back pain, is the largest single-site efficacy trial of spinal manipulative therapy. It has provided the strongest evidence to date on the short-term efficacy of spinal manipulative therapy. Our ORC research now serves as the basis for the American Osteopathic Association’s only clinical practice guideline, which addresses the use of OMT in patients with low back pain.


Over the years, the ORC mission has evolved to address issues that are relevant to health services and policy research and to primary care practice in general. Our present focus is on developing the Pain Registry for Epidemiological, Clinical, and Interventional Studies and Innovation (PRECISION) as a resource to study the natural history of low back pain, and to assess prevention and treatment options based on the biopsychosocial model and emerging aspects of precision medicine. This research is presently supported through grants from the Osteopathic Heritage Foundation, American Osteopathic Association, and Institute for Patient Safety.



The Osteopathic Research Center is pleased to participate in a landmark $14 million NIH study of low back pain


Do You Have Low Back Pain?

We invite you to join our research registry for people with low back pain. To enroll in the registry, known as PRECISION TEXAS, you will be asked to answer questions approximately every three months. You will also be asked to provide one-time saliva and blood samples for analysis of DNA, proteins and other biological substances. If you qualify to participate, there will be an initial visit to the University of North Texas Health Science Center campus in Fort Worth’s Cultural District. Regular follow-ups will be conducted in person, by telephone or online. You will be compensated for your time and travel in the form of a gift card. You must be between the ages of 21 years and 79 years, and may not be pregnant to enroll in this registry. To learn more, please call 817-735-5410 or email us at orcstudyoperations@unthsc.edu.


Screening Questionnaire for the PRECISION Pain Research Registry


This page was last modified on September 13, 2018