Osteopathic Research Center

dr. licciardone reviewing a document with the surgeon general

Dr. Licciardone presenting osteopathic research data to former U.S. Surgeon General Regina Benjamin.

a doctor at a microscope

Dr. Hodge conducting lymphatic pump research in her laboratory.

The Osteopathic Research Center (ORC) was founded in 2002 to serve as a profession-wide research center for osteopathic medicine. The original mission of the ORC was to conduct research on the mechanistic and clinical aspects of osteopathic manipulative treatment (OMT). In so doing, the ORC has provided important evidence through systematic reviews, meta-analyses, and randomized controlled trials. The OSTEOPATHIC Trial, completed in 2011 and involving 455 patients with chronic low back pain, is the largest single-site efficacy trial of spinal manipulative therapy. It has provided the strongest evidence to date on the short-term efficacy of spinal manipulative therapy. Our ORC research now serves as the basis for the American Osteopathic Association’s only clinical practice guideline, which addresses the use of OMT in patients with low back pain.


Over the years, the ORC mission has evolved to address issues that are relevant to health services and policy research and to primary care practice in general. Our present focus is on developing the Pain Registry for Epidemiological, Clinical, and Interventional Studies and Innovation (PRECISION Pain Research Registry) as a resource to study the natural history of low back pain, and to assess prevention and treatment options based on the biopsychosocial model and emerging aspects of precision medicine. This research is presently supported through grants from the Osteopathic Heritage Foundation, American Osteopathic Association, and SaferCare Texas.

Effective May 1, 2019, we are expanding our PRECISION Pain Research Registry operations to cover major cities throughout Texas. We will not be enrolling any new participants or collecting data during this transition process. Please check back with us on June 3, 2019.


Congratulations to six members of the TCOM Class of 2022 who have been accepted as new Clinical Research Fellows by the PRECISION Pain Research Registry.


The Osteopathic Research Center is pleased to participate in a landmark $14 million NIH study of low back pain.


ORC researcher is recognized as the leading worldwide authority on osteopathic manipulation by Expertscape.


This page was last modified on April 30, 2019