The OSTEOPATHIC Trial

The OSTEOPATHIC Trial was completed by the Osteopathic Research Center in 2011. The study assessed the efficacy of osteopathic manipulative treatment in 455 patients with chronic low back pain. Over a dozen publications have reported on the OSTEOPATHIC Trial, including the most recent studies on substantial improvement and recovery and from chronic low back pain with osteopathic manipulative treatment. A partial list of accessible publications is provided below.

Licciardone JC, Gatchel RJ. Nonpharmacologic Therapies for Low Back Pain. Ann Intern Med. 2017 Oct;167(8):606-607. Available here

Licciardone JC, Gatchel RJ, Aryal S. Targeting Patient Subgroups With Chronic Low Back Pain for Osteopathic Manipulative Treatment: Responder Analyses From a Randomized Controlled Trial. J Am Osteopath Assoc. 2016 Mar;116(3):156-68. Available here  

Licciardone JC, Gatchel RJ, Aryal S. Recovery from Chronic Low Back Pain After Osteopathic Manipulative Treatment: A Randomized Controlled Trial. J Am Osteopath Assoc. 2016 Mar;116(3):144-55. Available here    

Licciardone, C. John, Aryal, Subhash. Clinical response and relapse in patients with chronic low back painfollowing osteopathic manual treatment: Results from the OSTEOPATHIC Trial. Man Ther. 2014 May 15. Available here 

Licciardone, C. John, Kearns, M Cathleen, Crow, W. Thomas. Changes in biomechanical dysfunction and low back pain reduction with osteopathic manual treatment: Results from the OSTEOPATHIC Trial. Man Ther. 2013 Sept 10. Available here 

Licciardone, C. John. Short-term dosing of manual therapies for chronic low back pain. The Spine J. 2014 June. Available  here 

Licciardone, C. John, Kearns, M Cathleen, Minotti, E. Dennis. Outcomes of osteopathic manual treatment for chronic low back pain according to baseline pain severity: Results from the OSTEOPATHIC Trial. Man Ther. 2013 Feb 6. Available here

Licciardone, C. John. Kearns, M Cathleen, Hodge, M. Lisa, Minotti, E. Dennis. Osteopathic manual treatment in patients with diabetes mellitus and comorbid chronic low back pain: Subgroup results from the OSTEOPATHIC Trial. J Am Osteopath Assoc. 2013 Jan 10; Available here 

Licciardone, C. John, Minotti, E. Dennis, Gatchel, J. Robert, Kearns, M Cathleen, Singh, P. Karen. Osteopathic manual treatment and ultrasound therapy for chronic low back pain: A randomized control trial. Ann Fam Med. 2013 March. Available here  

Licciardone, C. John, Gatchel, J. Robert, Kearns, M Cathleen, Minotti, E. Dennis. Depression, somatization and somatic dysfunction in patients with nonspecific chronic low back pain: Results from the OSTEOPATHIC Trial. J Am Osteopath Assoc. 2012 June 18. Available here  

Licciardone, C. John, Kearns, M Cathleen, Hodge, M. Lisa, Bergamini. V.W. Michael. Associations of cytokine concentrations with key osteopathic lesions and clinical outcomes in patients with nonspecific chronic low back pain: Results from the OSTEOPATHIC Trial. J Am Osteopath Assoc. 2012 Mar 30. Available here 

Licciardone, C. John, Kearns, M Cathleen. Somatic dysfunction and its association with chronic low back pain, back-specific functioning, and general health: Results from the OSTEOPATHIC Trial. J Am Osteopath Assoc. 2012 Mar 15. Available here 

Licciardone JC, King HH, Hensel KL, Williams DG. OSTEOPAThic Health outcomes In Chronic low back pain: The OSTEOPATHIC Trial. Osteopath Med Prim Care 2008; 2:5 Available here  

This page was last modified on August 22, 2019