For Members

IACUC Responsibilities

Post-Approval Monitoring (PAM)

Reviewer Tip

According to the Animal Welfare Act and the PHS Policy, the IACUC is responsible for the following:

• • Program Review
  • Facility Inspection
  • Evaluation of Reports
  • Investigate Concerns
  • Make Recommendations
  • Review Protocols
  • Review Significant Changes
  • Authorized to Suspend Animal Activity

Provides continual IACUC Oversight for the animal care and use program. Examples of PAM includes: 

• • Tracking the acquisition of animals
  • Semi-Annual Inspections
  • Protocol and laboratory audits
  • Observation of procedures 
  • Regular review of adverse or unexpected experimental outcomes affecting the animals. 
  • Examination of surgical areas and records
  • Review of protocol related health and safety issues

The following special considerations should be given when reviewing protocols: 

• • Experimental and Humane Endpoints
  • Unexpected Outcomes
  • Physical Restraint
  • Multiple Survival Surgeries
  • Food & Fluid Regulation
  • Non-Pharmaceutical Grade Substances
  • Field Investigations
  • Agricultural Animals