50 Heroes: Dr. Sid O’Bryant

Sid O'bryant

Nearly two decades ago, Dr. Sid O’Bryant set out to develop a blood test to detect Alzheimer’s disease at the earliest stage possible.

Today, the first study of a blood test to detect Alzheimer’s disease within a primary care setting is underway at The University of North Texas Health Science Center at Fort Worth.

The simple test would be a game-changer in the diagnosis of early Alzheimer’s and if successful, could detect the disease earlier, easier and at a lower cost, said Dr. O’Bryant, Executive Director of the Institute for Translational Research and Dr. Joe and Peggy Schooler Endowed Chair in Pharmacology and Neuroscience.

As one of the world’s leading experts in blood-based biomarkers of Alzheimer’s and other neurodegenerative diseases, Dr. O’Bryant is dedicated to bringing novel diagnostics and innovative treatments to those with Down syndrome, Lewy Body disease and Parkinson’s disease.

Robert McClain, PhD, Associate Vice President Research & Development, praised Dr. O’Bryant for his dedication.

“Dr. O’Bryant is a true innovator in every sense of the word and a role model for advancing translational research to meet unmet medical needs,” he said.

He is also a global leader in health disparities in brain aging. He leads the one-of-a-kind Health & Aging Brain among Latino Elders (HABLE) study, which is the most comprehensive study of Mexican-American brain aging to date.

Through HABLE, he and his team have assessed nearly 1,000 older Mexican Americans. The study will determine if the underlying causes for Alzheimer’s disease vary between racial and ethnic groups so appropriate precision medicine therapies can be created.


50th Anniversary Logo

Honor your HSC hero today! Please make a tribute gift, submit a photo or share a story that you value.

Join us throughout 2020 as we celebrate the people, events and innovations that made UNTHSC all it is today — and look ahead to the next 50 years.

For the 50th anniversary, team members nominated people whose contributions make them HSC Heroes. Each week, a new Hero will be revealed.

View the list of all our Hero profiles published so far this year. There is a new one each week.

Recent News

Techstars Demo Day.
  • On Campus
|Dec 1, 2022

Techstars Demo Day brings innovation to the historic stockyards

For the last 13 weeks, the founders of 10 of the world’s most innovative startups have been in Fort Worth perfecting their new physical health technology. They are part of the world’s first physical health accelerator, and now they are ready to show the fruits of their labor. Techstars Demo D...
Dr. Sid O'bryant Award
  • Our People
|Dec 1, 2022

HSC named the winner of the D Magazines 2022 Achievement in Medical Research Award

The extensive research done by Dr. Sid O’Bryant and his team at the Institute of Translational Research has earned the University of North Texas Health Science Center at Fort Worth the 2022 Medical Research Award by D Magazine. Dr. O’Bryant, the executive director of the ITR and a professor at t...
Dr. John Licciardone
  • Our People
|Nov 30, 2022

Key study results from HSC’s PRECISION Pain Research Registry published in JAMA Network Open

The Journal of the American Medical Association – Network Open has published findings from a recent HSC study about chronic lower back pain, race and the patient-physician relationship. The study revealed that Black patients reported worse outcomes for low back pain intensity and back-related d...
Ram flyer
  • Community
|Nov 23, 2022

Free pop-up medical, vision and dental clinic is just a week away

  The University of North Texas Health Science Center at Fort Worth and Remote Area Medical – RAM® — a nonprofit provider of pop-up clinics that delivers free quality dental, vision and medical care to those in need — are bringing the free health care clinic to Dallas on Dec. 3 and 4....