Guidelines bring Alzheimer’s blood test one step closer

SID-BLOOD-RESEARCH-WEBA simple blood test to detect early Alzheimer’s disease is a step closer to being used to screen older adults.

Detailed standardized guidelines that are needed before a blood test could be used in practice have been published in Alzheimer’s & Dementia. The guidelines establish protocols and reflect the continued efforts of an international working group that includes UNT Health Science Center.

“If we are ever going to get a blood test for Alzheimer’s disease into the hands of primary care providers, we must have guidelines,” said Sid O’Bryant, PhD, Interim Director of the Institute of Aging and Alzheimer’s Disease Research.

The highly rigid guidelines will be used in research for blood-based biomarkers of Alzheimer’s disease and will ensure every lab is following the same procedures when collecting blood, said Dr. O’Bryant, a member of the group and lead author of the paper.

“You can create a blood test in the lab, but if you don’t have a systemized way for collecting the blood, the test will never go into practice,” he said. “You’ll have one lab doing it one way and another lab doing something different.”

Dr. O’Bryant has worked for several years with representatives from across the United States, Australia, Germany, England and other countries to create the standards. Everything from the type of needle used to draw blood to the length of the storage time is specified in the guidelines.

Just as with blood tests for other diseases, such as diabetes, protocols must be established to make sure every lab performs the test exactly the same. Such guidelines are needed before FDA approval can be sought to use the test in a clinical setting.

“For UNTHSC, our next step is take these blood guidelines and implement them into a clinical trial,” Dr. O’Bryant said. “That’s never been done before.”

Recent News

7281bfad 8597 4cef 80de B58ea8a26ab5
  • Community
|Jun 10, 2024

North Texas Asthma Summit to improve asthma outcomes for children

Representatives from 10 North Texas organizations will come together Wednesday with one common goal in mind: improving health outcomes for children with poorly controlled asthma. The goal of the North Texas Asthma Summit is to develop community partnerships to help these children who frequently e...
Dobbs Headshot
  • Our People
|Jun 7, 2024

School of Health Professions welcomes three new staff members

The University of North Texas Health Science Center at Fort Worth’s School of Health Professions is excited to announce three new staff members in the dean’s office. Christa Lo, DHSc, MPAS, PA-C, joins SHP as associate dean. In her role, she will assist in overseeing the school’s academic...
Drwhite
  • Our People
|Jun 6, 2024

TCOM Alumnus Dr. Frederick White receives the Gold Medal Award for Distinguished Service from the AOCR

In recognition of his outstanding leadership, dedication and service, Frederick E. White, DO, FAOCR, a 1977 graduate from the Texas College of Osteopathic Medicine at The University of North Texas Health Science Center at Fort Worth, was selected as the recipient of the American Osteopathic College ...
Hampton 5
  • On Campus
|Jun 5, 2024

Hampton University representatives visit HSC to build partnerships

A delegation of five representatives from Hampton University visited The University of North Texas Health Science Center at Fort Worth’s campus on Friday. Hampton University is a private, historically Black university founded in 1868 in Hampton, Virginia. The group included President of Ham...