Epidemiologic Research Methods and Causal Inference

Assessing the effect of an exposure on outcome requires rigorous methods to rule out random error, confounding, misclassification, and/or selection biases as possible alternative explanations.

• Dr. Uyen-Sa D. T. Nguyen

Choi HK, Nguyen US, Niu J, Danaei G, Zhang Y. Selection bias in rheumatic disease research. Nat Rev Rheumatol. 2014 Jul;10(7):403-12. PMCID: PMC4260806.

Nguyen UD, Zhang Y, Louie-Gao Q, Niu J, Felson DT,  LaValley MP, Choi HK. The obesity paradox in recurrent attacks of gout in observational studies: Clarifications and remedy. Arthritis Care Res (Hoboken). 2017 Apr;69(4):561-566. doi: 10.1002/acr.22954. PubMed PMID: 27331767; PubMed Central PMCID: PMC5179319.

Wang Y, Nguyen UDT, Lane NE, Lu N, Wei J, Lei G, Zeng C, Zhang Y. Knee osteoarthritis, potential mediators, and risk of all-cause mortality: data from the Osteoarthritis Initiative. Arthritis Care & Research (Hoboken). 2020 Jan. doi: 10.1002/acr.24151 Epub 2021 Mar 13. PMID: 31961495; PMCID: PMC8606227.