ACLM Evidence chart

Evidence supports a positive effect on health outcomes

Target Patient
A. Obesity B. Hypertension C. Dyslipidemia D. Impaired Glucose Tolerance
Metabolic Syndrome
E. Type 2 Diabetes F. Cardiovascular Disease G. Stroke H. Heart Failure I. Peripheral Artery Disease J. Chronic Obstructive
Pulmonary Disease
K. Osteoarthritis L. Rheumatoid Arthritis M. Cancer – All N. Breast Cancer Prostate cancer O. Osteoporosis P. Depression Q. Fibromyalgia R. Chronic Fatigue Syndrome S. Type 1 Diabetes T. Non-alcoholic fatty U. Multiple Sclerosis V. Parkinson’s W. Cognitive Impairment
X. Chronic Low Back Pain Evidence supports physicians
can affect behavioral changes
Exercise X X O X X X X X X O X O X O X X X O X O O O X X
Diet/Nutrition X X X O X X O O
Stress Reduction O
Smoking Cessation O O O X
Alcohol Moderation X O
Multiple Behaviors X X X X X O X O X O O


X = Evidence includes randomized controlled trials support.

O = Evidence is limited to observational studies.

X/O = Evidence based on literature not cited in literature review.

  1. Manikonda JP, Stork S, TogelS, et al, Contemplative Meditation reduces ambulatory blood pressure and stress induced hypertension: a randomized pilot trial; Jouranl of Human Hypertension, 2007, 1-3.
  2. Ornish D, Magbanua MJM, Weidner G. Changes in prostate gene expression in men undergoing an intensive nutrition and lifestyle intervention. PNAS, 2008; 105 (24): 8369-8374.
  3. Grandes G, Sanchez A, Sanchez-Pinilla RO, Torcal J, et al. for the PEPAF Group Effectiveness of Physical Activity Advice and Prescription by Physicians in Routine Primary Care: A Cluster Randomized Trial. Arch Intern Med. 2009;169(7):694-701

This page was last modified on January 22, 2016