Protecting astronauts’ immune systems during spaceflight

By Alex Branch

Long-time collaborators UNT Health Science Center and Langston University have teamed with NASA on a five-year project to study the effects of reduced gravity on astronauts’ immune systems during spaceflight.

Harlan Jones
Harlan Jones, PhD

The project, funded by a $4.5 million NASA grant, also is intended to promote diversity in the field of space biomedicine, said Harlan Jones, PhD, Assistant Professor in the UNTHSC Institute of Molecular Medicine and Director of the Center for Diversity and International Programs. Students from Langston, the state of Oklahoma’s only historically African-American university, have for years participated in the Health Science Center’s 10-week summer internship research program.

The NASA project will focus on natural approaches that could help avoid dysregulation of astronauts’ immune systems.

During space flight, some of astronauts’ immune cells can become less active while others become more active, according to a 2014 NASA study. Reduced cell activity can prevent the immune system from generating appropriate responses to threats, while heightened activity can result in increased allergy symptoms or persistent rashes. On a long spaceflight, even a cold or the flu can be risky business for astronauts, the study reported.

Dr. Jones and Langston faculty and students will have opportunities to work on the project with NASA scientists in laboratories at Johnson Space Center in Houston.

“I’m an immunologist, and the faculty at Langston are very interested in developing natural products that could perhaps improve the performance of astronauts’ immune system on long space flights, such as NASA’s goal of a mission that reaches Mars,” said Dr. Jones, co-investigator on the project. “It’s a unique research opportunity for both faculty and students.”

The project also supports NASA’s Office of Education goal of ensuring that underrepresented and underserved students participate in NASA education and research projects in their pursuit of science, technology, engineering and math (also known as STEM) careers.

UNTHSC provides Langston University faculty and students with professional development opportunities, mentorship, grant-writing training and access to a doctoral program in biomedical research. Dr. Jones also is assisting Langston University with development and strengthening the university’s research labs, also funded by the NASA grant.

“Participation in such as project ensures that we prepare an ever-increasing diverse demographic with the demand for a talented pool to compete in the global STEM career workforce,” Dr. Jones said.

Recent News

Clearfield
  • Our People
|Sep 29, 2023

Dr. Michael Clearfield the inaugural winner of the Beyer, Everett, and Luibel Memorial Medal

For more than two decades, Dr. Michael B. Clearfield, DO, MACOI, FACP, has developed the Department of Internal Medicine and Geriatrics at the Texas College of Osteopathic Medicine into one of the largest and most productive academically in the osteopathic profession, serving as the chair from 1982-...
Kari Northeim 2 (002)[66]
  • Our People
|Sep 28, 2023

HSC’s Dr. Kari Northeim and Parker County collaborators awarded SAMHSA grant for rural EMS training and education

Dr. Kari Northeim, School of Public Health assistant professor of population and community health at The University of North Texas Health Science Center at Fort Worth, has been awarded the SAMHSA Rural EMS Training and Education grant in conjunction with HSC community partners, Parker County Hospi...
Graci Finco
  • Research
|Sep 28, 2023

SBS researchers publish innovative study in Nature Scientific Reports 

People with leg amputations, including those with diabetes, run the risk of overuse injuries like osteoarthritis, muscle atrophy or bone breaks in their intact limbs.   Now, new research is quantifying the impacts of amputations and diabetes, a leading cause of amputation, on those overuse ...
Frank Filipetto Cropped For Social
  • On Campus
|Sep 28, 2023

HSC’s Texas College of Osteopathic Medicine to host symposium on ‘Creating Change in Health Care Delivery’

Americans have soured on the U.S. health care system, according to a Gallup poll taken earlier this year. Most of those surveyed rate health care quality as subpar, including 31% saying it is “only fair” and 21% — a new high — calling it “poor.” The U.S. ranked nearly last compared w...