CHOLESTEROL-LOWERING MEDICINE UNDER REVIEW AT HEALTH SCIENCE CENTER

January 28, 2000

FORT WORTH – Texas â?? A cholesterol-lowering medication is being studied at the UNT Health Science Center and researchers are seeking patients who have evidence of vascular disease and an LDL cholesterol level of greater than 160 mg/d to enroll in the study.

The study medication, which is a type of statin, is currently not available through physicians or pharmacies. According to Dr. Michael Clearfield, chief of internal medicine and primary investigator for the study, the purpose of the study is to test this new medicine against the strongest cholesterol-lowering drug currently available. Researchers hope this new statin will be more effective in lowering cholesterol. Dr. Martin Weiss, cardiologist with the health science center, is also a co-investigator.

Cholesterol is a fatty substance in the body which, in high levels, is associated with an increased risk of heart disease and stroke. Extra cholesterol in the blood collects in the inner walls of the arteries, allowing less blood to get to the heart.

According to Dr. Clearfield, the higher your total cholesterol number, the higher the risk for heart disease. In this study those with an LDL cholesterol of over 160 mg/dl are being sought. Most people with an LDL over 160 mg/dl would expect to have a total cholesterol over 220 mg/dl.

Cholesterol travels in the blood in packages called lipoproteins. Cholesterol packaged in low-density lipoprotein (LDL) is often called “bad” cholesterol, because too much LDL in blood can lead to cholesterol buildup and blockage in the arteries. An LDL level of 100 mg/dL or lower is desirable for people with vascular disease, such as those in this study.

The study is being conducted in over 30 centers in the United States. Health science center researchers will be seeking study participants for several months.

All research study-related medication, tests and exams will be provided free of charge. In many cases, volunteers are compensated for their time and travel expenses. Those interested can discuss clinical research participation with their doctor and call the Office of Clinical Trials at (817) 735-0256.

Heath Fc
Protecting her daughters’ generation from Alzheimer’s

By Alex Branch Janet Heath has a deeply personal interest in Alzheimer’s disease. Her mother suffered from it, as did her grandmother. Heath spent the last 10 years of her mother’s life trying to coordinate high-quality care as the disease took its terrible toll. That’s why Heath and ...Read more

Jul 17, 2018

Sid Fc
A blood test that IDs Alzheimer’s earlier, easier and cheaper

By Jan Jarvis   The first study of a blood test to detect Alzheimer’s disease within a primary care setting soon will be conducted at UNT Health Science Center. The simple test could be a game-changer in the diagnosis of early Alzheimer’s. If successful, it would be possible to ide...Read more

Jul 12, 2018

Dr. Taylor
New Provost: Let’s ‘unleash our strengths and ignite our future’

By Jeff Carlton Charles Taylor, PharmD, who has presided over a number of critical academic milestones as Dean of the UNT System College of Pharmacy, will become Provost and Executive Vice President of Academic Affairs at UNT Health Science Center. Dr. Taylor said he was “excited, honore...Read more

Jul 11, 2018

campus FC
UNTHSC to close July 4 for Independence Day

The UNT Health Science Center, all clinics staffed by UNT Health physicians, and the Fitness Center will be closed on Wednesday, July 4, 2018, for the Independence Day holiday. The Lewis Library will be open, with abbreviated hours on July 3 and 4. Have a safe and healthy Independence Day!...Read more

Jul 3, 2018