A wider window for treating stroke
When someone has a stroke, there’s a very narrow window – three hours or less –when the drug tPA can be used to dissolve blood clots and restore blood flow.
But few people benefit from this treatment because they don’t get care fast enough, said Shaohua Yang, PhD, MD, Professor of Pharmacology and Neuroscience.
By widening this window, it may be possible to prevent the long-term consequences of a stroke.
“Damage to the brain from a stroke can trigger long-term memory loss and dementia downstream,” he said.
A $103,000 grant from the American Heart Association is not only helping Dr. Yang better understand how to prevent the consequences of stroke, it also is raising UNT Health Science Center’s profile as a leader in stroke research.
Despite the highly competitive environment that exists in grant funding, stroke research has expanded at UNTHSC. Over the last two years, the American Heart Association has awarded four grants to young scientists in Pharmacology and Neuroscience.
Over the last decade, research has led to improvements in the survival rate for stroke patients. Once the second-leading cause of death in the United States, stroke now ranks fifth. But there’s been little improvement in long-term outcomes.
“We can treat the acute stroke, but the long-term consequences are much more severe, and we don’t have much to offer patients,” Dr. Yang said.
More than 800,000 patients suffer a stroke annually. Between 25 percent and 30 percent of stroke survivors develop dementia, often within the first year of recovery. Having a stroke doubles the risk of developing dementia.
Expanding the treatment window might be one way to prevent or slow dementia and improve the quality of life for patients, Dr. Yang said.
By Sally Crocker UNTHSC students, faculty and staff are invited to the 2nd Annual Zoonotic Disease Fair from noon to 3 p.m. on Nov. 21 to learn about some of the common diseases found in Texas that can be passed from animals to humans. “It pays to be aware,” said public health st...Read more
Nov 16, 2017
By Alex Branch Amy Raines Milenkov, MPH, DrPH, has always cared about the underdog. She cared about the low-income women and children afflicted with HIV or AIDS who she helped as a social worker in the 1990s, when life-saving drug cocktails were only emerging. She cared for the vu...Read more
Nov 13, 2017
By Jan Jarvis Catherine Daniel, a first-year student in the Texas College of Osteopathic Medicine, clicked on the keys of her laptop, searching for data about a program to address infant mortality in Tarrant County. “There needs to be a better way of identifying high risk people,” she ...Read more
Nov 13, 2017
By Alex Branch Gary and Aundrea Palladino met while serving in the U.S. Air Force as pharmacy technicians at Joint Base Andrews in Washington, D.C. At the three pharmacies on base, Gary and Aundrea filled prescriptions and managed inventory, compounded IV and topical medication orders, and...Read more
Nov 9, 2017