Department of Physiology & Anatomy
Trevor A. Day, Ph.D.
Professor of Physiology, Department of Biology
Mount Royal University
“Integration of Respiratory and Renal Responses to Acute and Chronic Blood Gas Challenges – Novel Insights and Future Directions”
Blood gases (PO2 and PCO2) and acid-base variables (e.g., pH) are maintained within narrow ranges, supporting the metabolic rate. However, blood gases are challenged by various atmospheric, recreational, and occupational contexts, where O2 can be low (hypoxia) and/or CO2 can be low (hypocapnia) or high (hypercapnia), perturbing arterial pH. The feedback control of breathing and renal acid-base regulation are mediated through complex coordination and interactions between the respiratory and renal systems to maintain blood gas and acid-base homeostasis in the face of acute and chronic blood gas challenges, such as exposure to high altitude. In this talk, we will explore the integration of respiratory and renal responses to acute and chronic blood gas challenges and illustrate some novel insights and future directions.
Friday, September 2, 2022, 11:00AM-12:00PM, LIB-110
University of North Texas Health Science Center
Fort Worth, Texas