Seeking Research Participants!

This is an advertisement seeking volunteers to participate in a research study entitled:

?The Role of Accentuated Antagonism in Cold Induced Pain Mediated Sympathoexcitation?

The University of North Texas Health Science Center (UNTHSC) is looking for up to 60 subjects in total to take part in a study that will assess various cardiovascular parameters during immersing a hand in cold water and applying neck suction with and without infusion of intravenous metoprolol. Maximal aerobic exercise testing may be performed if you are recruited into a specific subset of this study.

You must be 18-80 years old. We are recruiting individuals affected with Obstructive Sleep Apnea (OSA) at all stages of treatment, highly fit and normal healthy subjects.

Risks of the study are slight, but include and are not limited to: numbness/paresthesia in area of electrode insertion site, uncomfortable sensation from immersing the hand in ice water, bruising due to venous catheter insertion and adverse drug reaction. Study personnel are willing to address any concerns about risks associated with participation over the phone, in person or by email.

Study Requirements:
? Visit the laboratory in the Department of Integrative Physiology at UNTHSC on 2 separate days.
o One Familiarization session; up to 2 hours
o One Experimental session; approx. 2-3 hours.

Participation in this study is voluntary, and if you are a student or employee of UNTHSC your participation (or non-participation) in this study will in no way affect your academic standing or employment. Subjects will be compensated for their time and effort

If you are interested in participating in this study as a research subject, please contact Noah Jouett via email (noah.jouett@live.unthsc.edu) or phone (817-735-0219)