Deadlines
Letter of Intent: May 13, 2025
Final Submission: September 3, 2025
Description
Patient Centered Outcomes Research Institute
PCORI is interested in patient-centered CER of clinical interventions and health system strategies that focus on community-based and hospital-based interventions to address violence and trauma. Of note, studies with an intervention arm that solely involves utilization of a community health worker (CHW) or a patient navigator will be considered nonresponsive; however, it will be acceptable to embed CHW outreach or patient navigation into patient-centered CER study questions that address social needs and integrate these professionals as part of a broader organizational intervention strategy for violence and trauma.
This Topical PCORI Funding Announcement (PFA) is exclusively dedicated to funding high-quality, patient-centered comparative clinical effectiveness research (CER) projects that address violence and trauma within the following 3 Special Areas of Emphasis only:
- Intentional Trauma: Projects must focus on one or more of the following populations:
- Individuals affected by intimate partner violence.
- Children and youth who have experienced abuse.
- Older adults subjected to abuse or neglect.
- Unintentional Trauma: Research must specifically target:
- Patients with traumatic brain injury (TBI).
- Care models for fall prevention and fall recovery among older adults.
- Impaired mobility and physical function resulting from unintentional trauma.
- Substance Use and Trauma: Studies must compare existing strategies for pain management aimed at reducing susceptibility to substance use disorder (SUD) in the context of traumatic injury treatment.
Proposals must align with one or more of these three Special Areas of Emphasis. Applications that do not explicitly address these areas will be considered nonresponsive. Further details on each area are provided below and in the full PFA.
For more information, please see the opportunity webpage.