Funding Opportunity Number: RFA-DA-25-013
Letter of Intent: February 13, 2024
Submission: March 13, 2024
Award Amount: Up to $250,000.
The NOFO invites applications to investigate the underlying mechanisms and CNS consequences of the interactions of addictive substances and HIV-1 infection on inflammasome assembly and activation. It is important to understand how the involvement of myeloid cell-regulated inflammasome activation, interactions between myeloid cells and neurons, as well as other CNS resident cells, impact processes such as HIV-1 infection, latency, or disease progression among substance using populations.
Basic and preclinical research projects are appropriate. Substances of interest include: opioids, nicotine, cocaine, methamphetamine, stimulants, psychedelics, addictive prescription drugs, cannabinoids, or combinations of these substances.
The NOFO invites applications to investigate the underlying mechanisms and CNS consequences of myeloid cell-triggered inflammasome activation in the context of comorbid HIV-1 infection and acute or chronic substance use,
For more information, please see the funding opportunity website.