Evaluation of microvascular oxygenation during central hypovolemia with Resonance Raman Spectroscopy and Visible Light Spectroscopy

The University of North Texas Health Science Center is looking for 20 subjects to take part in a study that will assess microvascular oxygen levels on your mouth, hand, forehead, temple, and ear-lobe during a test of simulated bleeding using a technique called “lower body negative pressure”

You must be: -Healthy, non-nicotine user (cigarettes, chewing tobacco, nicotine patch) -Aged between 18-45 years

Study Requirements: -Visit the laboratory in the Department of Integrative Physiology & Anatomy at UNTHSC on 2 separate days -Day 1: familiarization session; 1-2 hours -Day 2: experimental session; up to 4 hours -Participation in this study is voluntary, and if you are a student or employee of UNTHSC your participation (or non-participation) will in no way affect your academic standing or employment -Subjects will be compensated for their time and effort

If you are interested in participating in this study as a research subject, please contact Dr. Caroline Rickards via email (caroline.rickards@unthsc.edu) or phone (817-735-2735)