The FY24 Defense Appropriations Act provides funding for the Glioblastoma Research Program (GBMRP) to support research of high potential impact and exceptional scientific merit to reduce the burden of glioblastoma on Service Members and their Families, Veterans and the American public. The managing agent for the anticipated program announcements/funding opportunities is the CDMRP at the U.S. Army Medical Research and Development Command (USAMRDC).
The GBMRP is providing the information in this pre-announcement to allow investigators time to plan and develop ideas for submission to the anticipated FY24 funding opportunities. This pre-announcement should not be construed as an obligation by the government. The FY24 GBMRP funding opportunity announcements for the following award mechanisms will be posted on the Grants.gov website. Pre-application and application deadlines will be available when the announcements are released.
Applications submitted to the FY24 GBMRP must address one or more of the following Focus Areas, not all of which will be applicable to every mechanism:
- Hypothesis Development Award:
- Biomarkers:
- Identification and development of promising biomarkers for glioblastoma. Biomarkers may include, but are not limited to, susceptibility/risk, diagnostic or prognostic, monitoring/disease progression, predictive, therapeutic response, or safety biomarkers. Noninvasive or minimally invasive strategies and technologies are encouraged.
- Drug Delivery:
- Strategies and technologies for increased therapeutic efficacy and reduced toxicity including chemical, molecular, or mechanical delivery approaches with consideration of overcoming the blood-brain barrier and increasing access to the central nervous system.
- Biomarkers:
- Resource Development Award:
- Models
- Enhanced development, characterization, and validation of novel disease models that accurately recapitulate glioblastoma pathobiology, particularly the immune component and disease recurrence or progression.
- Models
A pre-application is required and must be submitted through the electronic Biomedical Research Application Portal (eBRAP) at https://eBRAP.org prior to the pre-application deadline. All applications must conform to the final funding opportunity announcements that will be available for downloading from the Grants.gov website. The application package containing the required forms for each award mechanism will also be found on Grants.gov. A listing of all CDMRP and other USAMRDC extramural funding opportunities can be obtained on the Grants.gov website by performing a basic search using CFDA Number 12.420.
Submission deadlines are not available until the funding opportunity announcements are released. For email notification when announcements are released, subscribe to program-specific news and updates under “Email Subscriptions” on the eBRAP homepage at https://eBRAP.org. For more information about the GBMRP or other CDMRP-administered programs, please visit the CDMRP website (https://cdmrp.health.mil).