Babu Padanilam, Ph.D.
Professor & Director of Kidney Research, Milton & Carroll Petrie
Department of Urology
Icahn School of Medicine at Mount Sinai
“Pathophysiology of Acute Kidney Injury and its progression to CKD.”
Babu Padanilam, Ph.D., is Professor and Director of Kidney Research in the Department of Urology at the Mount Sinai School of Medicine. Babu has had a long-standing interest in various aspects of cellular injury and regeneration mechanisms in the injured kidney. In NIH supported projects, his laboratory is studying the mechanisms of cellular injury in acute kidney injury (AKI) and renal fibrogenesis in chronic kidney disease (CKD) models. The molecular mechanisms leading to energy depletion and cell death in the kidney proximal tubules, are investigated in various experimental models of AKI. Significant risks for long term loss of renal function and development of renal fibrosis and progression to CKD exists after AKI. He is currently studying the regulation of fatty acid oxidation in AKI, role of sympathetic nerve activity, neural factors and epoxyeicosatrienoic acids (EETs) in the regulation of renal fibrogenesis in different models of CKD. In collaborative projects, the laboratory is 1) developing novel drug delivery approaches in AKI and CKD 2) characterizing a novel mouse model of congenital obstructive nephropathy and 3) elucidating mechanisms leading to hemodynamic alterations in hypertension and diabetes.
Friday, March 24, 2023, 11:00AM-12:00PM, EAD-108
University of North Texas Health Science Center
Fort Worth, Texas