Clinical Trial / Intervention Design and Efficacy Evaluation

Intervention development and evaluation involve dynamic and iterative processes which can include conceptualizing and designing interventions, feasibility, pilot or efficacy testing, as well as full-scale effectiveness and implementation trials.

Related Faculty

• Dr. Ashenafi S Cherkos
• Dr. Gregory Knell
• Dr. Eun-Young Mun
• Dr. Scott Walters

• Brayton RP, Price AM, Jones C, Ellis C, Burkhart S, Knell G. Prospective evaluation of 24-hour movement behaviors among adolescents recovering from a sport-related concussion.Applied Neuropsychology: Child, 1-9. doi; 10.1080/21622965.2023.2181082
• Knell G, Burkhart SO, Gabriel KP. Need to clarify mechanisms explaining the effect of screen time on recovery from concussion. JAMA Pediatrics. Published online 2021 Dec 13; doi: doi:10.1001/jamapediatrics.2021.5339.
• Knell G, Caze II TJ, Burkhart SO. Evaluation of the vestibular and ocular motor screening (VOMS) as a prognostic tool for protracted recovery following paediatric sports-related concussion. BMJ Open Sport Exerc Med. 2021;7(1):e000970. doi: 10.1136/bmjsem-2020-000970. eCollection 2021. PubMed PMID: 33868706; PubMed Central PMCID: PMC7996664..
• Businelle, M. S., Walters, S. T., Mun, E-Y., Kirchner, T. R., Hebert, E. T., & Li, X. (2020). Reducing drinking among people experiencing homelessness: protocol for the development and testing of a just-in-time adaptive intervention. JMIR Research Protocols, 9(4), e15610.
• Chung, T., Bae, S. W., Mun, E.-Y., Suffoletto, B., Jang, S., & Dey, A. (2020). Mobile assessment of acute effects of marijuana on cognitive functioning in young adults: A pilot study. JMIR mHealth and uHealth, 8(3), e16240
• Larimer, M. E., Witkiewitz, K., Schwebel, F. J., Lee, C. M., Lewis, M. A., Kilmer, J. R., Andersson, C., Johnsson, K., Dillworth, T., Fossos-Wong, N., Pace, T., Grazioli, V. S., & Berglund, M. (2021). An International Comparison of a Web-Based Personalized Feedback Intervention for Alcohol Use During the Transition out of High School in the United States and Sweden. Prevention Science, 22, 670-682. DOI: 10.1007/s11121-021-01231-w
• Lee, C. M., Cadigan, J., Kilmer, J, Cronce, J., Suffoletto, B., Walter, T., Fleming, C., & Lewis, M. A. (2021). Brief Alcohol Screening and Intervention for Community College Students (BASICCS): Feasibility and Preliminary Efficacy of Web-conferencing BASICCS and Supporting Automated Text Messages. Psychology of Addictive Behaviors, 35, 840-851. DOI: 10.1037/adb0000745
• Lewis, M. A., Rhew, I. C., Fairlie, A. M., Swanson, A. Anderson, J. & Kaysen, D. L. (2019). Evaluating personalized feedback intervention framing with a randomized controlled trial to reduce young adult alcohol-related sexual risk taking. Prevention Science, 310-320. doi.org/10.1007/s11121-018-0879-4
• Lewis, M. A., Patrick, M. E., Litt, D. M., Blayney, J. A., Atkins, D. C., Kim, T., Norris, J., George, W. H., & Larimer, M. E. (2014). Randomized controlled trial of a web-delivered personalized normative feedback intervention to reduce alcohol-related risky sexual behavior. Journal of Consulting and Clinical Psychology, 82, 429-440. 10.1037/a0035550 PMCID: PMC4029925
• Lewis, M. A., Litt, D. M., Fairlie, A. M., Kilmer, J. R., Kannard, E., Resendiz, R., & Walker, T. (2022). Investigating Why and How Young Adults Utilize Protective Behavioral Strategies for Alcohol and Marijuana Use: Protocol for Developing a Randomized Controlled Trial. JMIR Research Protocols, 11, e37106.
• Ray, A. E., Mun, E.-Y., Lewis, M. A., Litt, D. M., Stapleton, J. L., Tan, L., Buller, D., Zhou, Z., Bush, H., & Himelhoch, S. S. (2023). Cross-tailoring integrative alcohol and risky sex feedback for college students: A hybrid type 1 effectiveness-implementation trial. JMIR Research Protocols, 12, e43986.
• Litt, D. M., Geusens, F., Seamster, A., & Lewis, M. A. (2022). A parent-based intervention for reducing high-risk social media cognitions, alcohol use, and negative consequences among adolescents: Protocol for a randomized controlled pilot study. JMIR Research Protocols, 11, e38543.
• Mun, E.-Y., von Eye, A., & White, H. R. (2009). An SEM approach for the evaluation of intervention effects using pre-post-post designs. Structural Equation Modeling, 16(2), 315-337.
• Walters, S. T., Ondersma, S. J., Ingersoll, K. S., Rodriguez, M., Lerch, J., Rossheim, M. E., & Taxman, F. S. (2014). MAPIT: Development of a web-based intervention targeting substance abuse treatment in the criminal justice system. Journal of Substance Abuse Treatment, 46, 60-65.
• Walters, S. T., Mun, E.-Y., Tan, Z., Luningham, J. M., Hebert, E., Oliver, J. A., & Businelle, M. S. (2022). Feasibility and preliminary effectiveness of a smartphone-based just-in-time adaptive intervention for adults with alcohol misuse who are experiencing homelessness. Alcoholism: Clinical and Experimental Research. https://doi.org/10.1111/acer.14908