Available Instrumentation

Examples of Collaborative Services and Available Instrumentation in the UNT System College of Pharmacy

NMR Spectrometer Identify and characterize chemicals and compounds via 1H and 13C spectroscopy (1D and 2D)
TOF LC/MS Identify chemical reaction products; verify compound identity via accurate mass for small molecules
QQQ LC/MS Pharmacokinetic and pharmacodynamic studies of small molecules; other UHPLC applications where mass spectrometry detection of small molecules is required
Lyophilizer Remove aqueous solvents from sample(s) by freeze drying
Powder X-ray Diffractometer Analytical technique primarily used for phase identification of a crystalline material and can provide information on unit cell dimensions
UV/Vis Spectrophotometer UV/Vis spectral analysis (cuvette)
Varian HPLC with Shimadzu UV Detector and HP Integrator Qualitative and quantitative analysis of chemical reactions and biochemical experiments as well as semi-preparative and preparative purification of compounds
Dissolution Test System Dissolution testing of drug formulations
Vertical Diffusion System In vitro permeation studies for transdermal drug research
Zetasizer Ultra Particle Analyzer Particle characterization
Mastersizer 3000E Particle Analyzer Particle size distribution analysis by dynamic light scattering (DLS) on particles from 0.1µM up to 1000µm
RT-PCR System Amplify DNA, quantitate DNA and mRNA
ChemiDoc Imaging System UV/Vis detection and documentation for gel/Western imaging; DNA, RNA and protein analysis
Odyssey IR Scanner Near IR (NIR) Western blot detection, also in-cell and on-cell Westerns, and visualization of Syto 60-stained nucleic acids in gels
Biological Safety Cabinet Work space for culturing mammalian cells as well as experiments involving biohazardous materials
CO2 Incubators Culture cells for biochemical and pharmaceutical experiments
Inverted-Stage Microscope with Digital Camera Visual monitoring and digital documentation of cell cultures
Vi-Cell Analyzer Determine cell number, cell size and cell viability using cuvettes
Image Cytometer Determine cell number, cell size and cell viability using slide- based counting chambers
Fluorescence Microscopy Digital photographic documentation and histological analysis of cultured cells and tissues
Multi-Mode Microplate Reader Fluorescence, UV/Vis absorbance and luminescence-based microplate assays
Centrifuges Centrifugation for cell culture and sample preparation
Dual-injector luminometer Glow- and flash-based bioluminescence assays in 96-well plates
Water Purification Systems Reagent quality water required for cell culture, chemical and biochemical experiments, and spectrophotometric analyses
OpenSPR Surface plasmon resonance for binding kinetics and affinity studies
FTIR Spectrometer Infrared spectral analysis
Differential Scanning Calorimeter Thermoanalysis of compounds to provide structural information useful for compound identification and characterization
Thermogravimetric Analyzer Method of thermal analysis in which the mass of a sample is measured over time as the temperature changes.

 

The Pharmaceutical Analysis Core Lab utilizes iLab for managing instrument reservations, use and fee-for-service requests. To register for an iLab account, please visit https://unthsc.ilab.agilent.com.
For more information please contact:
Donna Coyle Jianmei Wang
817-735-0688 817-735-0679
Donna.Coyle@unthsc.edu Jianmei.Wang@unthsc.edu

 
3500 Camp Bowie Blvd
Fort Worth, Texas 76107