UNT Health Science Center
Sid E. O’Bryant, PhD

Sid O’Bryant, PhD

Professor - Pharmacology & Neuroscience
Pharmacology & Neuroscience
Research interests:This line of work is important for our community and for society. Our goal is to revolutionize geriatric medicine with better diagnostics and better treatment.

As the population of those aged 65 and over continues to grow, so does the concern over related health issues. Dr. Sid O'Bryant established a translational aging research platform in the Department of Internal Medicine to work collaboratively throughout the campus. And as the lead of an international working group, Dr. O’Bryant joins a group of scientists from across the globe who are dedicated to bringing cures and innovative treatments to those who suffer from Alzheimer's and age-related diseases.

The concept of translational aging research bridges teams from across all disciplines to further the discovery process. As the champion of this collaborative effort focused on aging, Dr. O’Bryant’s work spans both global and cultural boundaries.

Indeed, while he is a renowned international speaker, Dr. O’Bryant is quick to point to the work his team is achieving in Fort Worth. Through the HABLE (Health & Aging Brain among Latino Elders) study, he and his team have assessed more than 500 Latino elders (primarily Mexican American), providing valuable information to an all-too-often underserved segment of the community. He realizes that the epidemic of memory loss crosses every culture, and as the Hispanic population grows, it represents one of the greatest areas of need.

In 2010, Dr. O’Bryant and his colleagues generated and validated a blood-based proteomic profile that yields excellent diagnostic accuracy in detecting Alzheimer's disease. This will allow primary care physicians to determine which elderly patients should be referred for specialty assessment. The next step in this process is testing the blood test within primary care clinics.

For this work, Dr. O'Bryant received the Federation of Associations in Behavioral Health & Brain Science (FABBS) Early Career Impact Award (for first 10 years’ work post-PhD). In doing so, he became the first person nominated for the award by the National Academy of Neuropsychology.

A strong believer in the importance of educating the next generation of translational scientists, Dr. O’Bryant’s team engages post graduate, graduate, undergraduate and even high school trainees in their research and outreach efforts.
Academic:Neuropsychology Postdoctoral Fellowship, New Orleans VA Medical Center

Doctor of Philosophy, Clinical Psychology, Clinical Neuropsychology Specialization, University at Albany, State University of New York - Albany

Predoctoral Clinical Psychology Internship, University of Mississippi Medical Center / Jackson VA Consortium

Master’s Degree, Clinical Psychology, University at Albany, State University of New York - Albany

Bachelor of Science, Psychology, Louisiana State University


Honors:Current – Member, Leadership Team

Current – Inaugural Chair, Blood Based Biomarker Professional Interest Area of the International Society to Advance Alzheimer’s Research & Treatment (ISTAART)

2014 – Early Career Service Award, National Academy of Neuropsychology

2013 – Early Career Investigator Award, Federation of Associations in Behavioral & Brain Sciences (FABBS)

2012 – 40 Under 40 for Fort Worth, Fort Worth Business Press

2010 – Chancellor's Distinguished Research Award, TTUHSC

2010 – Fellow, National Academy of Neuropsychology

2009 – Early Career Award, National Academy of Neuropsychology